Principal Scientist, Medicinal Chemistry

MOMA Therapeutics

Allston, MA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Post Date: 06/02/2021
  • Website:
  • Company Address: 215 First Street, Suite 150, Cambridge, MA, 02142

About MOMA Therapeutics

We’re on a mission to unlock molecular machines by understanding and respecting their complexities. We’ll be working incredibly hard to discover their untapped potential because we believe they are the key to delivering the next generation of precision medicines. We are unapologetically scientific, and we know this will help us achieve our mission to get new medicines to people in need. We’ve removed the bureaucracy and believe having a teammate’s back is critical to our success. You see, MOMA isn’t your typical biotech company. We are drug discovery professionals, industry specialists and scientific experts. More importantly, we’re collectively unstoppable.

Job Description

Imagine joining a company where you…. 

  • Will be part of an experienced and resilient team that is collectively unstoppable, trusts one another, and selflessly collaborates 
  • Will be part of a group comprised of incredible humans who are committed to the discovery of transformative medicines for cancer patients 
  • Can be the CEO of your own role and master of your own craft 
  • Are needed… because the work you will do is critical to the success of the company, and because patients are counting on you 

About MOMA Therapeutics 

At MOMA Therapeutics, we are discovering the next generation of medicines. We are motivated by a single common goal, to discover and develop innovative new medicines for patients through our singular focus: the therapeutic targeting of molecular machines.  

In this role you will..

  • Lead the implementation and management of all medicinal chemistry strategies to achieve project / research goals
  • Effectively interface with medicinal chemistry and project teams to ensure transparency and alignment
  • Pilot the selection of critical path activities to drive project progression
  • Be responsible for managing outsourced synthetic chemistry at partner CROs
  • Effectively communicate new project proposals, medicinal chemistry strategies, innovative ideas and results
  • Work collaboratively across diverse functions to achieve corporate goals


  • A PhD degree in organic/medicinal chemistry is required, in addition to 5+ years of drug discovery experience in a pharmaceutical/biotechnology setting
  • Self-starter with demonstrated leadership in medicinal chemistry and drug discovery as evidenced by performance and accomplishment
  • Demonstrated track record of success in the progression of drug discovery programs
  • Experience implementing medicinal chemistry strategies across all stages of project progression from hit identification, hit to lead evaluation, and lead optimization to achieve program goals
  • Experience functioning within strong multi-disciplinary teams and utilizing cross-functional information, such as biochemical activity, ADME, structural biology, and pharmacological data, to drive medicinal chemistry strategies;
  • Demonstrated technical skills and scientific creativity in organic and medicinal chemistry
  • Demonstrated experience in complex problem solving through in depth analysis of data 
  • Experience in managing external chemistry teams


  • Strong leadership and collaboration skills and a proven track record of success in applying innovative ideas to both existing projects and new project selection
  • The ability to lead both internal and external medicinal chemistry teams and significantly impact interdisciplinary project teams 
  • At home in a results-driven, highly accountable environment where you can make a clear impact
  • A team player, who listens effectively and invites response and discussion
  • A collaborator who communicates in an open, clear, complete, timely and consistent manner


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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.