SRA/RA 2, Medicinal Chemistry

RAPT Therapeutics

South San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Post Date: 06/07/2021
  • Website: rapt.com
  • Company Address: 561 Eccles Avenue, South San Francisco, CA, 94080

About RAPT Therapeutics

RAPT Therapeutics is a clinical stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in oncology and inflammatory diseases. Utilizing its proprietary discovery and development engine, the company develops highly selective small molecules that are designed to modulate the fundamental immune responses underlying these diseases. RAPT has rapidly discovered and advanced two unique drug candidates each targeting CCR4, including our lead oncology drug candidate, FLX475, now in clinical development and our lead inflammation drug candidate, RPT193, expected to enter the clinic in the second half of 2019. The company is also pursuing other discovery targets including GCN2 and HPK1 for the treatment of cancer.

Job Description

SUMMARY OF POSITION: The Research Associate/Senior Research Associate will be responsible for synthesizing novel molecules directed at one of our biological targets.  He/She will be a key member of a multi-disciplinary drug discovery team and develop a broad working knowledge of various scientific disciplines in addition to medicinal chemistry including immunology, oncology, and drug metabolism. With guidance from their supervisor and project leadership, the Research Associate will integrate data from previously synthesized molecules into the design of novel molecules anticipated to possess increasingly optimal biological profiles.
 
 
ESSENTIAL DUTIES AND JOB FUNCTIONS: 
• Contribute to the research team by synthesizing key intermediates and small molecule drug targets.
• Carry out purification and characterization of compounds.
• Maintain clear and accurate records of experiments in approved notebooks.
• Develop a broad working knowledge of medicinal chemistry, including principles of drug design, pharmacology, and drug metabolism, among others.
• Integrate data from previously synthesized molecules into the design of molecules anticipated to possess superior profiles.
• Help maintain the efficiency of the drug discovery organization through activities such as inventory management, equipment maintenance, etc. as needed.
 
 
KNOWLEDGE, EXPERIENCE AND SKILLS:
• BS or MS in organic chemistry with minimum of 2 years of synthetic chemistry experience.
• Excellent oral and written communication skills. 
• Experience working in a fast-paced lab environment.
• Industry experience a plus.
 
About RAPT Therapeutics RAPT Therapeutics is a biotechnology company with an unrelenting determination and passionate drive to employ its expertise in immunology, small molecule drug discovery and computational biology to conquer cancer and inflammatory diseases. The company is led by a group of seasoned researchers from the biotechnology and pharmaceutical industries and is supported by several of the nation’s premier life sciences venture capital firms. The company is located in the San Francisco Bay area, in the heart of the world’s largest biotechnology research hub. We offer a competitive compensation and benefits package, including aggressive participation in the growth of the company in the form of stock option grants.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.