Senior Director of Research

Inhalon Biopharma

Durham, NC, US
  • Job Type: Full-Time
  • Function: Marketing/PR/Product Mktg
  • Post Date: 05/27/2021
  • Website: www.inhalon.com
  • Company Address: , Carrboro, NC

About Inhalon Biopharma

Inhalon Biopharma is a rapidly growing startup with a patented breakthrough technology for preventing and treating acute respiratory infections such as respiratory syncytial virus (RSV), metapneumovirus (MPV) and SARS-CoV-2. The Company just completed a Seed round and has been awarded funding by the US Army to run a Phase 1/2a study in COVID-19 patients and has multiple NIH/SBIR grants to develop its pipeline of treatments for RSV, MPV, and influenza. Inhalon operates out of Durham, NC and the SF Bay Area. The Company plans to start a Phase 1/2a COVID-19 study in early 2021 and file an IND for its RSV+MPV program in 2H 2021. We are looking for an energetic head of research and development to lead these programs into the clinic and build out the Company’s pipeline.

Job Description

Reporting to the Chief Development Officer and closely interacting with the regulatory, clinical development, translational, and process development teams, the Senior Director of Research will perform a critical role in guiding and executing the pre-clinical and translational strategy for the Company. Key functions will include design, coordination and execution for in vitro and in vivo monitoring assays performed both in-house and with third-party contractors in support of the ongoing and planned clinical trials. In addition, the role will have oversight responsibilities to the new product development group and the interface with the CMC/clinical/translational development teams as well as oversee the company wet-lab activities designed to catalyze and support drug candidate development.  This role has a high level of complexity requiring wide technical and scientific expertise; involving multiple techniques, projects and interfaces. The candidate must be able to demonstrate a track record of successful management experience, preferably in the context of a biologics-based, anti-viral focused, corporate environment. 

 

About Inhalon Biopharma

Inhalon Biopharma is a rapidly growing startup with a patented breakthrough technology for preventing and treating acute respiratory infections such as respiratory syncytial virus (RSV), metapneumovirus (MPV) and SARS-CoV-2. The Company just completed a Seed round and has been awarded funding by the US Army to run a Phase 1/2a study in COVID-19 patients and has multiple NIH/SBIR grants to develop its pipeline of treatments for RSV, MPV, and influenza. Inhalon operates out of Durham, NC and the SF Bay Area.

 

Essential Duties and Responsibilities

 

The Senior Director of Research will also be responsible for communicating very complex immunological and inhalation concepts to potential out-sourcing partner and stakeholders.  Thus, she/he should have excellent communications skills and possess the ability to translate complex science to groups who may not possess a strong scientific background.

 

  1. Be a team-player who can successfully interface with both the executive management team as well as with Development (CMC, Regulatory, Clinical) groups. Outstanding communication skills, including the ability to distill complicated scientific data into lay-language are critical for success in this role. 

  2. Design and execute complex development programs requiring highly organized data collection and management with phase appropriate quality and regulatory oversight.

  3. Contribute to key executive management activities for the successful execution of company strategy.

  4. Establish and have working operational knowledge for key analytical and selection methods (inhalation, manufacturing and functional assay cell line development, upstream and downstream processing of recombinant proteins, recombinant molecular biology techniques) to support in-house development and characterization of candidate biologics for inhalation.         

  5. Support transition of new candidates from R&D to Clinical evaluation:   

    • Manufacturing cell line development and analytical characterization

    • Research cell bank manufacturing, characterization & testing

    • Cell culture platform evaluation and development

    • Analytical fit-for-purpose assays and studies associated with inhalation technology and characterization

  6. Develop anti-viral, immunological and mucosal functional assays for key company projects.

  7. Collect and analyze data and maintain quality compliant records of laboratory research and development.

  8. Prepare data for technical reports, publications and grants.

  9. Author technical documentation (reports, abstracts and manuscripts) from both basic pre-clinical development as well as clinical response data.

  10. Interact with multiple colleagues in a dynamic environment. Be willing to take on new projects outside the ‘normal’ course of business. Be highly motivated. 

  11. Meet with collaboration partners to communicate scientific progress.

 

This position may require domestic and/or international travel.

 

Qualifications/Requirements

 

Significant experience (15+ years) in immunology, virology and inhalation drug delivery with a thorough working knowledge of key assays is strongly preferred; and personnel management experience required. Candidates with corporate or biotech R&D management experience and publication histories is a must. The successful candidate should have laboratory experience in most or all of the following fields: mammalian cell culture (adherent and suspension), molecular biology techniques (PCR, sequencing, restriction mapping), genome analysis, bioanalysis (e.g. ELISA, assays of antiviral function and pulmonary delivery). Working knowledge of mucosal biology is advantageous.

 

A successful candidate must possess exceptional attention to detail, organizational, interpersonal, and communication skills, and demonstrate critical thinking and problem-solving skills. They must have the ability to perform several tasks simultaneously to meet critical deadlines and the independent initiative to solve interdisciplinary problems. Candidate must be sharp, self-motivated, and able to thrive in a fast-paced dynamic biotech environment where flexibility, tolerability to rapid change, and drive to make a significant impact is essential. He/she should have a flexible mind and thrive on generating creative problem-solving ideas. Must enjoy working in collaboration with others and small teams to achieve goals through effective building of relationships with co-workers.

Inhalon offers a competitive compensation and benefits package as well as an environment where your contributions can make a significant difference.

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This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.