San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Post Date: 05/03/2021
  • Website: nurix-inc.com
  • Company Address: 1700 Owens Street Suite 500, San Francisco, CA, 94158

About Nurix

Nurix Therapeutics discovers drugs that harness the body's natural process to control protein levels.

Our drugs control ubiquitin E3 ligases, the key enzymes responsible for protein breakdown in human cells, as a unique therapeutic approach to treat a broad range of diseases.

Our focus is on developing drugs to treat cancer including novel, small molecule immuno-oncology agents.

Job Description

We are seeking a researcher who is interested in working with scientists in our DNA-encoded chemical library (DEL) screening team to perform assays in support of our drug discovery process.  This work includes performing qPCR assays, Illumina next-generation sequencing (NGS) templates, and other molecular biology, protein biochemistry, and analytical biochemistry duties.

Required Qualification

The candidate we seek must have a degree in the life sciences with a strong background in biochemistry and molecular biology. Moreover, we are interested in someone who integrates well within a process-oriented team. The successful candidate should have very good organizational and communication skills. 

  • Experience: Two or more years of industry experience performing qPCR assays and preparing NGS sequencing samples
  • Specific Technical Proficiency in: qPCR assay (absolute method), PCR amplification reactions, DNA and protein quantitation, workflows involving multi-channel pipetting
  • Instrument Proficiency Desired: Real-time PCR instrumentation (QuantStudio7, Bio-Rad CFX384, etc.), Agilent TapeStation or Bioanalyzer, Nanodrop spectrophotometer, various plate readers, liquid chromatography-mass spectrometry a plus
  • Software Proficiency Required: Excel, Word, PowerPoint

Fit with Nurix Culture and Values

  • Strong team orientation; highly collaborative
  • Solutions and results-oriented focus
  • Hands-on approach; resourceful and open to diverse points of view 


Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix’s extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.