Associate Scientist, Translational Pharmacology

Korro Bio

Cambridge, MA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Post Date: 05/02/2021
  • Website: www.korrobio.com
  • Company Address: 400 Technology Sq, 10th Floor, Cambridge, Massachusetts, 02139

About Korro Bio

At Korro Bio our aim is to bring transformative treatments to patients with rare and debilitating diseases by addressing the underlying genetic cause. We are utilizing the precision provided by nucleic acid-based therapeutics to target the sequences responsible within the genetic code.

Job Description

Company Summary:   Korro Bio is a privately held biotechnology company launched out of a top-tier life science venture firm headquartered in Cambridge, Massachusetts. We are utilizing the precision provided by nucleic acid-based therapeutics to target the sequences responsible for inherited disorders within the genetic code. At Korro Bio, our aim is to bring transformative treatments to patients with rare and debilitating diseases by addressing the underlying genetic cause.

We are committed to investing in the personal and professional growth of our employees by putting work-life balance, family values and expanding an employee’s knowledge at the forefront. This has helped to shape us into an energetic, inclusive and innovative team where your value is celebrated no matter your role.  Together we intertwine our positive culture and intrinsic motivation with our passion for advancing science to directly impact the future of RNA editing one letter at a time.

Role Summary:

We are seeking a highly motivated Associate Scientist, Translational Pharmacology to join our team.  Reporting to the Director of Translational Pharmacology, the Associate Scientist will have the opportunity to work with an enthusiastic team of highly skilled scientists in a dynamic, high growth company.

KEY RESPONSIBILITIES

    Conduct experiments to determine the efficacy of novel compounds in models across a range of disease indications.
    Perform dosing (SC, IP and IV), monitor animal health, blood sampling, multiple tissue harvesting and data recording. Coordinate sample storage and analysis.
    Provide overall in vivo and ex vivo technical support for projects working to advance one or more experimental therapeutic compounds.
    Responsible for carefully documenting research and effectively communicating results across teams.
    Plan and execute in vivo studies in collaboration with research scientists.

EDUCATION AND SKILL REQUIREMENTS:

    BA/BS or MS with 3-5 years’ experience in the biotechnology or pharmaceutical industry or academic equivalent.
    Knowledge of tissue processing and molecular biology methods (RNA purification, PCR, qPCR, sequencing, ELISA (MSD) and western blot).
    Experience running mouse models, including mouse handling, health monitoring, dosing and working with models of disease is highly desired.
    Skilled in various methods of dosing (IV, SC and IP), blood collection (tail vein/submandibular and cardiac puncture) and multiple tissue collection at necropsy for subsequent ex vivo
    Desire and drive to learn and understand the basic biologic mechanisms underpinning our products.
    Experience in Oligonucleotide based therapeutics or gene editing is a plus
    Exposure to utilizing software such as Graph Pad Prism, Microsoft office, Excel, and electronic laboratory notebooks for data analysis and data summary.
    Excellent organizational, time management and data recording skills.
    Able to thrive in a highly collaborative, fast-paced, team-oriented environment with colleagues from diverse disciplines.
    Effective verbal and written communication skills.
    Detail-oriented and excellent problem-solving abilities.

Korro Bio offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401K retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.