Genomics Associate Scientist (Contract)

Insitro

South San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Post Date: 04/17/2021
  • Website: insitro.com
  • Company Address: 259 E Grand Ave, South San Francisco, California 94080, US

About Insitro

insitro is a data-driven drug discovery and development company that leverages machine learning and high-throughput biology to transform the way medicines are created to help patients.

At insitro, we are rethinking the entire drug discovery process, from the perspective of machine learning, human genetics, and high-throughput, quantitative biology. Over the past five decades, we have seen the development of new medicines becoming increasingly more difficult and expensive, leaving many patients with significant unmet need. We’re embarking on a new approach to drug development – one that leverages machine learning and unique in vitro strategies for modeling disease state and designing new therapeutic interventions. We aim to eliminate key bottlenecks in traditional drug discovery, so we can help more people sooner and at a much lower cost to the patient and the healthcare industry.

Job Description

The Opportunity

The heart of insitro’s strategy is the development of novel, cutting-edge methods in machine learning and high-throughput biology to address key bottlenecks in the drug development pipeline.  As a Genomics Associate Scientist, you will work to implement and execute genomic workflows, collaborating across multiple functions at insitro.  You will collaborate with scientists and engineers to develop, transfer and validate manual process steps to automated liquid handling and integrated systems. You will work to support efforts to improve the reproducibility and quality control tools on our high-throughput workflows. You will support the day-to-day activities for high-throughput molecular biology workflows ranging from RNA isolation to NGS-based QC.  In addition, you will support the development and operation of in-house sequencing and genomic assays, such as single cell and bulk RNA-seq. 

 

You will be joining as the founding team of a biotech startup that has long-term stability due to significant funding, but yet is very much in the startup phase. Due to the early and exciting phase of growth, there are ample opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us and help make a difference to patients!

 

About You

  • B.S./M.S. in biological sciences, bio/chemical engineering, or similar experience
  • At least 1 year of relevant work experience in academia or industry
  • Experience with Molecular Biology techniques including NGS prep, and DNA and RNA purification 
  • Experience with mammalian cell culture 
  • Experience creating documentation for process validation and standardized operating procedures
  • Excellent communication and organizational skills 
  • Excellent analytical and problem-solving skills
  • Familiarity with liquid handling systems 
  • Experience managing external services for sample processing and QC


Nice to Have

  • Experience with single cell RNA-seq/perturb-seq, ATAC-seq
  • Experience with CRISPR screening
  • Experience working with automated NGS library prep methods

 

Benefits at insitro

  • Excellent medical, dental, and vision coverage
  • Open vacation policy
  • Team lunches (catered daily)
  • Commuter benefits
  • Paid parental leave

 

About insitro

insitro is a data-driven drug discovery and development company using machine learning and data generation at scale to transform the way that drugs are discovered and delivered to patients. insitro’s approach focuses on the development of predictive machine learning models to be brought to bear on key bottlenecks in pharmaceutical R&D. The company has established enabling collaborations with Gilead in NASH and Bristol Myers Squibb in ALS. insitro is located in South San Francisco, CA and has been supported by top tech, biotech, and crossover investors since formation in 2018. For more information on insitro, please visit the company’s website at www.insitro.com.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.