Scientist I/II, Immune Oncology & In Vivo Pharmacology


South San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Post Date: 04/27/2021
  • Website:
  • Company Address: 630 Gateway Blvd, South San Francisco, CA, 94080-7014

About NGM Bio

NGM Bio is a research-driven, clinical-stage biopharmaceutical company with a passion to improve the lives of those struggling with serious diseases. Our expertise in drug discovery and translational development, coupled with the significant resources from our partnership with Merck, is driving development of transformational medicines that dramatically improve human health.

Job Description

NGM Biopharmaceuticals, Inc. is a biopharmaceutical company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases.  Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to build a company where innovation and cutting-edge science has provided the foundation for a robust drug discovery engine that has a track record of generating one new IND candidate per year.  NGM’s current pipeline of clinical-stage programs consists of five drug candidates targeting liver and metabolic diseases, retinal diseases and cancer.  The most advanced drug candidate, aldafermin (NGM282), is in Phase 2b clinical studies in non-alcoholic steatohepatitis (NASH) and is wholly-owned by NGM.  Another drug candidate, NGM621, is in a Phase 2 study in geographic atrophy (GA) secondary to age-related macular degeneration (AMD).  NGM’s strategic collaboration with Merck, with a current term running to March 2022, provides us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates. 
NGM is currently offering a unique opportunity for an organized and highly motivated Scientist I to join our team, focused on leading our immune oncology laboratory modeling efforts. An ideal candidate will be a soon-to-be or recent PhD graduate in the life sciences with a big-picture understanding of immune oncology and extensive tumor model handling experience; this role will involve coordinating all of our Immune Oncology Team's laboratory modeling efforts.


    • Designing and executing independent experiments 
    • Consistent critical review of scientific and patent literature 
    • Presenting to internal project teams and R&D Leadership 
    • Liaising with Commercial Research Organizations (CROs) and academic collaborators 
    • Leading select research meetings 
    • Working with a team to develop assays and perform experiments
    • Teaching techniques to collaborators and research associates


    • Extensive background in laboratory tumor models, including orthotopic models. Experience establishing and working with humanized tumor models highly desired
    • Substantial mammalian cell culture experience 
    • Proficiency in experimental design and execution 
    • Excellent communication skills, and ability to consistently understand and articulate scientific concepts and interpret data 
    • Experience with in vivo imaging techniques (such as IVIS imaging), and analysis and interpretation of imaging  
    • Proficiency in maintaining accurate and up-to-date laboratory records and skills in developing and managing team-wide laboratory in vivo data tracking systems. 
    • Excellent project management skills 
    • Well-versed in Excel and Graph Pad Prism


    • PhD in immunology / oncology related discipline including very strong laboratory experience with laboratory tumor models and 0-2 years of experience since graduating.
    • Track record of high-impact publications and presentations 
    • Deeply passionate about Biology and scientific discovery 
    • Strong self-motivation with a dedicated work ethic. 
    • Excellent oral presentation and communication skills. 
    • Previous experience with management of employees a plus

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.