( IHC ) Scientist, Analytical Sciences

Affinia Therapeutics

Waltham, MA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Post Date: 03/30/2021
  • Website: www.affiniatx.com
  • Company Address: Waltham, Massachusetts 02451, US

About Affinia Therapeutics

Affinia Therapeutics is working to transform gene therapy through a methodically designed proprietary platform. By engineering vectors and gene constructs, Affinia is building toward revolutionary treatments for devastating diseases.

Job Description

About the job

IHC Scientist, Analytical Sciences

 

Affinia Therapeutics is rapidly growing biotech company developing transformative gene therapies for devastating diseases. We are backed by a strong syndicate of life science investors and have ambitious plans to have a dramatic impact on the lives of patients around the world.

As an early employee you will play a key role in setting our culture and values. You will be working alongside the founding management team who have a track record of success in the industry. The pace of work is dynamic, fast and fun.

 

We are looking for a curious, organized and self-motivated individual to work with our team at Affinia. Team members work together to straddle the lines between research, development, and support. This is an excellent opportunity to gain experience and develop in a dynamic, next-generation gene therapy environment.

 

( IHC ) Scientist – Analytical Sciences

 

Affinia Therapeutics is seeking an experienced Histotechnologist to join our Analytical Science laboratory team. You will be part of a group dedicated to the advancement of therapeutic products based on vectors derived from our unique AAV therapeutic platform. As a member of the Analytical Sciences laboratory, you will contribute to the development of fit-for-purpose analytical assays to support our preclinical and translational activities, analyze samples and work cross-functionally with other laboratory groups to generate data and transfer methods as needed. You will contribute to evaluation of new analytical technologies and development of more efficient laboratory workflows to maintain a culture of quality and excellence.

This position is located at the Affinia Therapeutics site in Waltham, MA.

 

 Primary Responsibilities

 

  • Lead the development of fit-for-purpose histopathology and immunohistochemistry methods to support manufacturing, preclinical and translational activities. Perform analysis of samples using qualified analytical methods.
  • Execute validation activities for select analytical methods according to appropriate guidelines (GMP, GLP, GCP, ICH, CLSI). Coordinate transfer of qualified assay methods to cross-functional colleagues and CMO/CRO partners.
  • Execute method development, validation and testing to meet deadlines for program milestones.
  • Implement new laboratory workflows and continuous improvement efforts.
  • Mentor junior scientists and oversee day-to-day testing activities in the lab.

 

Minimum Qualifications

 

  • Ph.D., M.S. or equivalent degree in a relevant scientific area.
  • Minimum 6 years of industry experience developing histopathology and immunohistochemistry-based analytical methods.
  • Experience with tissue sectioning, automated staining platforms, confocal microscopy and digital image analysis software.
  • A strong record of demonstrating analytical reasoning and creative problem-solving skills in a laboratory environment, including common statistical analysis methods and software related to method development and validation.
  • Excellent written and oral communications skills, including experience writing laboratory SOPs, protocols and reports.

 

Preferred Qualifications

 

  • ASCP certification as a Histotechnician (HT) or Histotechnologist (HTL).
  • Previous experience working in a quality-regulated laboratory environment.
  • Previous experience managing junior scientists in the laboratory

 

 

 EEO Statement: Affinia Therapeutics is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.