Principal Technology Lead - Biotech AWS Solutions

Monte Rosa Therapeutics

Boston, MA, US
  • Job Type: Full-Time
  • Function: IT
  • Post Date: 04/03/2021
  • Website:
  • Company Address: 40 Guest St, Boston, MA, 02135

About Monte Rosa Therapeutics

Monte Rosa Therapeutics is a biotechnology company developing molecular glues to degrade disease-causing proteins by creating a platform that designs small molecules that reprogram ubiquitin ligases to eliminate disease drivers previously deemed undruggable.

Job Description

This is a technical hands-on leadership role reporting to the Head of Information Technology. The Principal Technology Lead is responsible for multiple aspects of Monte Rosa’s research technology platforms. The Information Technology group at Monte Rosa Therapeutics have an opportunity to shape our digital and cloud architecture to support our fellow researchers and scientists using cutting edge technology in pursuit of new drugs to ultimately help our patients. In partnership with the Data Science team and close collaboration with fellow scientists, the Principal Technology Lead will develop architecture, roadmaps, and operations of our research platforms (on-premises and Amazon Web Services). The right candidate will have experience with system design, support, and operations in a biotech environment.

Role Responsibilities:

  • Consult and support the application development team to help formulate a strategy to leverage solutions in AWS.
  • Collaborate and provide thought leadership in cloud technologies and champion a cloud first strategy.
  • Lead design discussions to translate business use cases into technical requirements and helping to design solutions to meet those requirements.
  • Collaborate to develop best in class application/service deployment suited for AWS.
  • Capture and share best-practice knowledge on AWS solutions architecture.
  • Researches and maintains knowledge in emerging technologies and possible application to the business.
  • Work with our engineers, vendors, and managed service provider to implement critical infrastructure and system components to support lab instruments and sensitive data.
  • Provide leadership, technology guidance and mentors others throughout the organization through effective communication, documentation, and architecture diagrams.





  • 5 – 10 years of experience as a principal engineer, architect, or technical lead, AWS Certification desired
  • 5+ years of Information Technology and research systems experience
  • Bachelor’s in computer science, related field, or equivalent demonstrable experience
  • Proven track record automating infrastructure processes on AWS
  • Scripting: Python, PowerShell
  • AWS Infrastructure: Datalakes, IAM, EC2, S3, EBS/EFS, ELB/ALB, AutoScaling, RDS and replication techniques, VPC, Subnets, Elastic IP, Route53, CloudWatch, CloudFront, Lambda, CloudFormation.
  • Excellent communications skills with the ability to convey cloud technologies and concept to all levels of audience will be important and willingness to collaborate and understand multiple viewpoints will be a must.
  • Experience designing and building high performance systems with scalability, availability, and fault-tolerance.
  • Hands on implementation experience with scripting languages (Ansible, Puppet, Chef).
  • Experience with systems, network, application security, and encryption
  • Experience with container technologies.
  • Experience with Infrastructure as Code and related technologies
  • Working in a Research, Pharmaceutical, and FDA regulated environment is a plus.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.