Senior Bioinformatician (Data Engineer)

SOPHiA GENETICS

Bordeaux, FR
  • Job Type: Full-Time
  • Function: Data Science
  • Post Date: 02/25/2021
  • Website: sophiagenetics.com
  • Company Address: 185 Dartmouth Street, Suite 502, Boston, MA, 02116

About SOPHiA GENETICS

SOPHiA GENETICS combines deep expertise in life sciences and medical disciplines with mathematical capabilities in data computing. Our mission is to bring data analytics solutions to market, to support healthcare professionals by maximizing the power of Data-Driven Medicine. We achieve this mission through the global adoption of SOPHiA AI, which is built using techniques such as statistical inference, pattern recognition and machine learning. This enables SOPHiA to provide equal benefits to all users, unite experts in a gold standard health tech platform, and motivate expert knowledge sharing for a sustainable impact on future patients.

Job Description

In our journey to impact on patients lifes, we are looking for a Senior Bioinformatician, Data Engineer, based in Bordeaux or Bidart.
We are primarily looking for passionate people. Seize the opportunity to contribute to a great cause, improving the diagnosis and treatment of serious illnesses, from Cancer to Genetic Diseases, within an outstanding company!

The position is open in the Tertiary analysis team. The team is transversal working across the main business lines of: Genomics, Radiomics and Clinical Trials. The primary focus of the team is the annotation of genetic variants (and other clinically relevant features) of patients and diseases. As such, the Tertiary analysis team identifies, handles and validates the contextual information supporting the clinicians in their interpretation of results.This includes (1) the design, evaluation and integration of predictive models and algorithms to prioritize variants and their effects, and (2) the integration of expert knowledge from multiple data resources and repositories.

The tasks are varied and cover a large array of topics, mainly covering the latter aspect.

More specifically, you will be involved in:

The identification and handling of biological metadata.

Contributions to the creation, population and maintenance of SOPHiA knowledge base for variants and their annotations.

Responsibilities:

    Conception and R&D of the backend solution for the management and integration of expert knowledge in the SOPHiA knowledge base (KB).
    Scientific and technical management of our extensive bioinformatics databases
        This will require the automation of variant database updating and integration of new data sources, including documentation and enabling design control of these processes.
        This will additionally involve manipulating data within postgreSQL / mySQL and other database structures
        The aim is to supply data as a service to both internal and external clients.
        This team coordinates with all data consumers to prioritize and organize accesses to — and maintenance of — external data services.
        This requires collaboration with different departments across the company including; Sales; Marketing; IT; Quality; Project Management and Product Management.

    The candidate will also participate in Bioinformatics based technical support, for our Alamut and SOHPiA DDM products.
    The Tertiary Operations Team is transversal involved numerous projects. Thus, the candidate would be required to document all activities and report developments in these projects to team leader, colleagues and project managers on a weekly basis.

Requirements

    PhD in a scientific field would be advantageous or a Masters with several years of experience.
    Competence in a widely used bioinformatics programming language, Python, R and Snakemake workflows would be an advantage.
    Linux bash scripting experience.
    Database experience in MySQL and postgreSQL.
    Ontologies development using tools such as SPARQL.
    Knowledge of Data Warehouses, Data Lakes and Lakehouses would be advantageous.
    Knowledge of Genetics and Molecular Biology. Experience in a clinical setting would be an advantage.
    Knowledge of variant annotation software and or concepts would be advantageous.
    Excellent communication skills, including experience in communicating complex scientific principles in simple terms.
    English is required.

Benefits

    An exciting journey to facilitate patients' access to better treatment worldwide
    Flexible, friendly and international working environment
    A stimulating technical environment
    Continuous learning and trainings
    Permanent exchanges with teams of experts within the company (AI, genomics, medicine, etc.)
    A competitive salary (35h + 4 additional weekly hours contract)


Starting date:  ASAP (or as agreed)

Contract type: Permanent full-time 

Application process : If you think you fit this position, please send a CV and a cover letter. Please note that incomplete applications will not be considered. 

After an initial screening process, candidates will be invited for remote interviews. You may be asked to perform a programming task as part of this process. Selected candidates will then be invited for personal interviews. 

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.