Senior Process Chemist

SAI Life Sciences

Cheshire, GB
  • Job Type: Full-Time
  • Function: Manufacturing
  • Post Date: 02/26/2021
  • Website: sailife.com
  • Company Address:

About SAI Life Sciences

Sai Life Sciences is built on the bedrock of partnership. We work with innovator pharma and biotech companies to accelerate the discovery, development and manufacture of complex small molecules for a healthier tomorrow. Our Vision is to support our global innovator partners bring 25 new medicines to life by 2025. And we are well on that journey.

Job Description

Sai Life Sciences is an expanding Contract Research & Development and Manufacturing Organisation
(CDMO) working with 7 of the top 10 pharma companies globally, as well as many leading smaller
biotechs. We work with our clients to accelerate the discovery, development and manufacture of
complex small molecules for a healthier tomorrow. With more than 2000 staff globally and ambitious
growth plans, our vision is to support our global innovator partners to bring 25 new medicines to life by
2025.

Marking the completion of 20 years since inception in 2019, the company began an organisation-wide
initiative to significantly expand and upgrade its R&D and manufacturing facilities, deepen scientific &
technological capabilities, strengthen automation and data systems, and above all raise the bar for
safety, quality and customer focus. Guided by the insights and feedback from its customers, it
committed to investing over US$150M between 2019 and 2023. Part of this investment in 2020 were
the new state of the art laboratories in our centre of excellence for process chemistry and analytical
development at the Alderley Park Biotech & Life Science Cluster, where we are now looking to
significantly expand both staff numbers and capabilities. Our team currently consists of 24 multidisciplinary scientists (chemists, analysts and engineers).

Non-GMP manufacture of kg quantities of intermediates and APIs is currently possible within our
bespoke Scale-up laboratory facility. During 2021 a new GMP Kilo-lab facility will be created capable of
multi-kg quantities of GMP API suitable for early phase clinical studies. The developed processes may
then be transferred to Sai’s manufacturing sites in India for further scale-up as required.
This is a great opportunity to work with an expanding global organisation and work closely with some of
the most innovative biotech and pharma companies on their most important programmes.

The Role

 You will join a team that identifies, develops and optimises synthetic routes to APIs, supporting
both early and late phase development.
 The successful candidate will have a background in Organic Chemistry combined with
demonstrated expertise in early, mid or late-phase route and process development for the
manufacture of APIs, intermediates and raw materials.
 Experience in any of route selection, process development and optimisation, quality by design,
technology transfer and commercial production would also be advantageous.
 The candidate is expected to lead chemistry projects as required to develop routes and
processes and then scale-up to manufacture.

Essential Requirements

 Higher or bachelor's degree in chemistry or related scientific discipline with several years'
relevant experience in a Process or Synthetic Chemistry environment.
 Experienced in the design of chemistry routes and processes for the scale-up of novel APIs,
intermediates and raw materials, working alongside analysts and engineers.
 A demonstrated ability to handle several projects in different stages of development at the
same time.
 In-depth, hands-on expertise and up-to-date knowledge of a wide range of organic chemistry
transformations.
 Strong scientific track record and project leadership experience

Key Roles and Responsibilities

 Lead, design and conduct laboratory experimentation to deliver customer projects.
 Deliver new routes and processes for early-phase APIs and intermediates to enable scale-up
to 35 L.
 Deliver optimised processes for mid and late-phase APIs and intermediates to enable scale-up
to pilot and production facilities in India.
 Working within multi-functional project teams operating to tight deadlines.
 Leading the chemistry aspects of projects as required.
 Maintain an organised and safe lab environment and encourage others to achieve the same.

Key Attributes

 Demonstrate learning agility in the use of new technologies and approaches to support
chemistry projects.
 Ability to solve complex scientific problems as part of a cross-functional team.
 Excellent communication; both verbal and written.
 A team player.
 Conscientious with a can-do attitude with good attention to detail.
 Good project management and supervisory / mentoring skills.

The Offer

 A competitive Salary and Benefits package including company pension, health and life
insurance, 25 days holiday per year and enhanced family leave.
 Work in a state-of-the-art facility on one of the country's leading Biotech & Life Science Parks.
 Flexible working hours and conditions to suit the right candidate.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.