Job Description
NOTE: ONLY APPLICANTS CURRENTLY RESIDING IN THE BAY AREA WILL BE CONSIDERED
Aligos Therapeutics, Inc. is a biotechnology company located in South San Francisco, California that is developing novel medicines to treat liver diseases in virology, inflammation/fibrosis and oncology. Aligos is pursuing the development of both oligonucleotide-based and small molecule therapeutics, each addressing major commercial market opportunities.
Reporting to the Senior Director, Clinical Development, the role has various responsibilities, including:
- Contributing to the design, implementation, interpretation, and presentation of clinical studies (including Ph1 first in human, clinical pharmacology studies) evaluating Aligos’ drug candidates
- Working collaboratively and effectively within each drug candidate’s project teams to ensure timely and successful execution of clinical studies
- Providing ongoing medical expertise, oversight, and team training for assigned studies, including:
- Performing regular data reviews (including PK, safety, efficacy) within, across studies
- Participating in dose escalation meetings to determine doses for subsequent cohorts
- Providing real time management of potentially important medical events related to drug candidates (e.g, serious adverse events or similar)
- Reviewing/drafting supporting technical/regulatory documents
- Communicating regularly and as needed pertinent information about these compounds to key internal stakeholders (e.g., SLT, BOD, Project Team) to facilitate decision making related to programs, corporate strategy, etc.
- Communicating with key external stakeholders to facilitate the development and medical oversight of these compounds. Stakeholders may include:
- Investigators, Medical Community (e.g., KOLs, presentation of abstracts/oral presentations at conferences, and writing of manuscripts)
- Safety Monitoring Boards
- Health Authorities
- Gaining/maintaining expertise in the biology and competitive landscape for Aligos’ therapeutic areas of interest and applying this knowledge to the development of assigned drug candidates
Qualifications
- A Medical Doctorate (MD, or equivalent) is required
- 3 years in clinical development at a pharmaceutical or biotechnology company is desired
- Experience in early clinical development, particularly with antiviral (especially Hepatitis B/C) or anti-infectious disease compounds is preferred
- Must have knowledge of (or be willing to complete training in) the Code of Federal Regulations related to clinical research, ICH GCP guidelines, and other applicable regulations and practices
- Working knowledge, understanding and application of principles, concepts and practices of clinical research, experimental design and statistical analysis is highly desired
- Excellent communication, organizational, and interpersonal skills required
- Ability to prioritize and handle multiple tasks and to facilitate and resolve cross-functional activities and issues required
- Must be flexible, open minded and adaptable to the changing needs and duties associated with this role in a small company
This position is located in South San Francisco and may require 20% travel once COVID-19 related travel restrictions are lifted.
