Medical Director, Clinical Development

Aligos Therapeutics

San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Operations
  • Post Date: 02/27/2021
  • Website: www.aligos.com
  • Company Address: 1 Corporate Dr., 2nd Floor, South San Francisco, CA, 94080

About Aligos Therapeutics

Aligos is developing targeted, curative therapies for hepatologic diseases and viral infections, including chronic hepatitis B virus, non-alcoholic steatohepatitis and hepatocellular carcinoma.

Job Description

NOTE: ONLY APPLICANTS CURRENTLY RESIDING IN THE BAY AREA WILL BE CONSIDERED

 

Aligos Therapeutics, Inc. is a biotechnology company located in South San Francisco, California that is developing novel medicines to treat liver diseases in virology, inflammation/fibrosis and oncology. Aligos is pursuing the development of both oligonucleotide-based and small molecule therapeutics, each addressing major commercial market opportunities.

 

Reporting to the Senior Director, Clinical Development, the role has various responsibilities, including:

 

  • Contributing to the design, implementation, interpretation, and presentation of clinical studies (including Ph1 first in human, clinical pharmacology studies) evaluating Aligos’ drug candidates
  • Working collaboratively and effectively within each drug candidate’s project teams to ensure timely and successful execution of clinical studies
  • Providing ongoing medical expertise, oversight, and team training for assigned studies, including:
  • Performing regular data reviews (including PK, safety, efficacy) within, across studies
  • Participating in dose escalation meetings to determine doses for subsequent cohorts
  • Providing real time management of potentially important medical events related to drug candidates (e.g, serious adverse events or similar)
  • Reviewing/drafting supporting technical/regulatory documents
  • Communicating regularly and as needed pertinent information about these compounds to key internal stakeholders (e.g., SLT, BOD, Project Team) to facilitate decision making related to programs, corporate strategy, etc.
  • Communicating with key external stakeholders to facilitate the development and medical oversight of these compounds. Stakeholders may include:
  • Investigators, Medical Community (e.g., KOLs, presentation of abstracts/oral presentations at conferences, and writing of manuscripts)
  • Safety Monitoring Boards
  • Health Authorities
  • Gaining/maintaining expertise in the biology and competitive landscape for Aligos’ therapeutic areas of interest and applying this knowledge to the development of assigned drug candidates

 

Qualifications

  • A Medical Doctorate (MD, or equivalent) is required
  • 3 years in clinical development at a pharmaceutical or biotechnology company is desired
  • Experience in early clinical development, particularly with antiviral (especially Hepatitis B/C) or anti-infectious disease compounds is preferred
  • Must have knowledge of (or be willing to complete training in) the Code of Federal Regulations related to clinical research, ICH GCP guidelines, and other applicable regulations and practices
  • Working knowledge, understanding and application of principles, concepts and practices of clinical research, experimental design and statistical analysis is highly desired
  • Excellent communication, organizational, and interpersonal skills required
  • Ability to prioritize and handle multiple tasks and to facilitate and resolve cross-functional activities and issues required
  • Must be flexible, open minded and adaptable to the changing needs and duties associated with this role in a small company

This position is located in South San Francisco and may require 20% travel once COVID-19 related travel restrictions are lifted.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.