Research Associate / Senior Research Associate, Lead Discovery

Remix Therapeutics

Cambridge, MA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Post Date: 12/30/2020
  • Website: www.remixtx.com
  • Company Address: One Kendall Square, Building 200, Cambridge, MA, 02139

About Remix Therapeutics

Remix Therapeutics is a biotechnology company developing novel small molecule therapies designed to reprogram RNA processing and treat disease in entirely new ways.

Job Description

Remix Therapeutics is a company focused on discovering modulators of RNA processing for undruggable disease drivers with the promise to bring new medicines to patients. We are developing a suite of proprietary platform technologies that transform our ability to design and develop therapeutics that can selectively modulate various steps of RNA processing biology. The company is financed by Atlas Venture, The Column Group, Foresight Capital, Arch Venture Partners, and Alexandria Venture Investments.


Position Summary:

We seek a highly motivated, experienced research associate to join our team located in Cambridge, MA. As a team member of the biomolecular sciences and lead discovery group, this individual will be responsible for the design, development, execution, and analysis of various multiplex screening assays monitoring gene regulation. The ideal candidate will have relevant experience in a drug discovery company and strong experimental skills. We are seeking enthusiastic scientists who can work independently, and as part of a team, in a dynamic innovative startup environment. The individual will be expected to contribute to data generation, analysis, interpretation, visualization as well as communicating with a cross-functional team of scientists.


Principal Duties and Responsibilities

  • Design, develop and implement a variety of cell-based assays to profile, screen, and characterize small molecule compounds (program support and HTS)
  • Develop in vitro assays for both high and medium throughput screenings for compound profiling and hit discovery (e.g. qPCR, luminescence reporter, high-throughput genomic technologies)
  • Improve and implement novel multiplex assays technologies for target and hit discovery
  • Maintain detailed records of experimental protocols and data in laboratory notebooks
  • Prioritize activities while balancing multiple priorities under time and resource constraints
  • Build and maintain productive relationships with colleagues in biomolecular sciences, biology, and chemistry

 
Qualifications

  • MS in cell/molecular biology or related discipline with 2-3 years of relevant industry or academic experience
  • Hands-on experience in designing, developing, performing and analyzing 384-well plate-based in vitro and cellular assays
  • Experience with qPCR, luminescence reporter and high-throughput genomic technologies desired but not essential
  • Familiar with next-generation sequencing (NGS) technologies
  • Experience with biophysical techniques desired (e.g. SPR, DSF, ITC) but not essential
  • Keen attention to detail and proven ability to manage timelines
  • Interpret, present and report research findings
  • Desire and ability to work in a multi-disciplinary team-focused environment

 
Remix values diversity and is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, marital or veteran status, genetic information, sexual orientation or any other legally protected status. Remix will make reasonable accommodations f
or qualified individuals with known disabilities, in accordance with applicable law.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.