Future Opportunity: (Senior) Machine Learning Engineer


South San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Data Science
  • Post Date: 01/08/2021
  • Website: insitro.com
  • Company Address: 259 E Grand Ave, South San Francisco, California 94080, US

About Insitro

insitro is a data-driven drug discovery and development company that leverages machine learning and high-throughput biology to transform the way medicines are created to help patients.

At insitro, we are rethinking the entire drug discovery process, from the perspective of machine learning, human genetics, and high-throughput, quantitative biology. Over the past five decades, we have seen the development of new medicines becoming increasingly more difficult and expensive, leaving many patients with significant unmet need. We’re embarking on a new approach to drug development – one that leverages machine learning and unique in vitro strategies for modeling disease state and designing new therapeutic interventions. We aim to eliminate key bottlenecks in traditional drug discovery, so we can help more people sooner and at a much lower cost to the patient and the healthcare industry.

Job Description

*Please note - this posting is for future opportunities and we will contact you should an opportunity arise that may be a good match.

The Opportunity

Machine learning lies at the core of insitro’s approach to rethinking drug development. As a machine learning engineer, you will lead the development of cutting edge machine learning methods that solve key problems in the drug development process. You will work closely with a cross-functional team of life scientists, bioengineers, and data scientists to identify areas where machine learning can make a difference, to conceptualize and develop biological datasets using cutting edge, high throughput platforms, and to analyze these data sets using the best machine learning methods, applied at scale. You will need to come up with novel methods that use a broad spectrum of machine learning approaches, including techniques at the forefront of the field. We aim to develop large data sets, and apply cutting edge machine learning methods; hence, you will need to develop and deploy machine learning methods at scale. You will work as part of a team to rigorously analyze our data, pull out key insights, and make accurate predictions that will let us quickly develop drugs that have high efficacy and low toxicity.    You will be joining as the founding team of a biotech startup that has long-term stability due to significant funding, but yet is very much in formation. A lot can change in this early and exciting phase, providing many opportunities for significant impact. You will work closely with a very talented team, learn a broad range of skills, and help shape insitro’s culture, strategic direction, and outcomes. Join us, and help make a difference to patients!   

About You

  • BS, MS, or Ph.D. in computer science, statistics, mathematics, physics, engineering, or equivalent practical experience
  • Expertise in one or more general-purpose programming languages (such as Python, C/C++, or Scala) 
  • Demonstrated ability to write high-quality, production-ready code (readable, well-tested, with well-designed APIs)
  • 4+ years of real-world work experience in software development for high-end machine learning algorithms
  • Significant experience with at least one high-end ML development environment (Tensorflow, Pytorch, Caffe, etc.)
  • Demonstrated ability to develop novel machine learning methods that go beyond putting together of existing code, and to apply problem-solving skills to complex issues
  • Ability to communicate effectively and collaborate with people of diverse backgrounds and job functions
  • Passion for making a difference in the world


Nice to Have 


  • Experience with biological data (DNA sequences, RNAseq, proteomics, microscopy images, etc.) 
  • Experience with scalable machine learning, including the application to large datasets (100TB+)
  • Proficiency in Linux environment (including shell scripting), experience with database languages (e.g., SQL, No-SQL) and experience with version control practices and tools (Git, Perforce, etc.)
  • Familiarity with cloud computing services (AWS or GCP)


Experience in these areas is highly valued but not required


  • Imaging and high content microscopy
  • Statistical Genetics
  • Functional genomics and epigenomics
  • Proteomics and small molecules modeling
  • Large-scale deep learning model training


Benefits at insitro


  • Excellent medical, dental, and vision coverage
  • Open vacation policy
  • Team lunches (catered daily)
  • Commuter benefits
  • Paid parental leave


About insitro


insitro is a data-driven drug discovery and development company using machine learning and high-throughput biology to transform the way that drugs are discovered and delivered to patients. The company is applying state-of-the-art technologies from bioengineering to create massive data sets that enable the power of modern machine learning methods to be brought to bear on key bottlenecks in pharmaceutical R&D. The resulting predictive models are used to accelerate target selection, to design and develop effective therapeutics, and to inform clinical strategy. insitro was launched in 2018 with a Series A of $100M funded by top investors including a16z, Arch Venture Partners, Foresite Capital, GV, and Third Rock Ventures. In 2019 the company announced a collaboration with Gilead Sciences in the area of NASH and, in mid 2020, announced a Series B financing of $143M including current investors and new investors Canada Pension Plan Investment Board (CPP Investments), T. Rowe Price, BlackRock, Casdin Capital and other leading investors. The company is located in South San Francisco, CA. For more information about insitro, please visit the company’s website at  www. insitro.com

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.