Senior Research Associate, Protein Engineering


South San Francisco, CA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Post Date: 04/22/2021
  • Website:
  • Company Address: 75 Shoreway Road, Suite C, San Carlos, CA, 94070-2727

About Atreca

Atreca is a biotechnology company that develops novel therapeutics through a deep understanding of the human immune response, with a focus on innovative novel cancer immunotherapeutics. With its Immune Repertoire Capture™ (IRC™) technology, Atreca has an unparalleled insight into how cancer patients’ immune responses can drive better clinical outcomes. Atreca was founded by scientists, industry experts, and investors who share the vision that unlocking the immune response of today’s patients is the key to creating a new generation of therapies.

Job Description

Atreca is an integrated biotechnology company located in South San Francisco, California (moving in 2021 to a new campus in San Carlos, CA). We apply our proprietary drug discovery platform to profile clinically relevant, active B cell responses in patients receiving successful treatment and, in turn, develop a portfolio of antibody therapeutics against novel tumor targets with the potential to treat large patient populations. Atreca seeks talented, driven individuals who are dedicated to making a positive impact on human health and are motivated to become key members of a growing biotechnology company.

Position Summary:

We are seeking an enthusiastic and motivated Senior Research Associate to join our Protein Engineering group. The successful candidate will play a key role producing and characterizing antibodies and engineered bispecifics in support of pre-clinical studies. This position will have the opportunity to interact and collaborate with a multidisciplinary team and utilize a variety of biophysical techniques to characterize novel therapeutics.

Duties & Responsibilities:

  • Scout small-scale productions and develop new purification methods to support scale ups of novel therapeutics (antibodies and bispecifics)
  • Produce and purify novel therapeutics at multi-Liter scale for use in pre-clinical studies
  • Develop and perform analytical methods, including SEC, IEX, HIC, MALS, BLI, SPR, Tm/Tagg and SLS/DLS
  • Catalog and integrate materials and results into informatics systems
  • Work with other project team members and communicate results with the team
  • Follow laboratory safety guidelines and practices

Required Skills and Qualifications:

  • MS in Cell Biology, Molecular Biology, Immunology, Bioengineering, etc., or BS/BA with 2+ years of relevant research experiences (industry experience preferred)
  • Experience with mammalian recombinant protein production required
  • Experience with FPLC, HPLC, SDS-PAGE required
  • Experience with HEK293 or CHO transient transfection preferred
  • Experience with bispecific antibodies a plus
  • Strong analytical skills, excellent communication skills, and attention to detail
  • Track record of being adaptable, self-motivated, and scientifically rigorous
  • Ability to work in a team, prioritize tasks, and drive projects to completion

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.