Lead Computational Scientist

Black Diamond Therapeutics

Cambridge, MA, US
  • Job Type: Full-Time
  • Function: Life Sciences R&D/Engineering
  • Post Date: 01/22/2021
  • Website: blackdiamondtherapeutics.com
  • Company Address: 25 HEALTH SCIENCES DRIVE, Stony Brook, NY, 1790

About Black Diamond Therapeutics

Black Diamond Therapeutics Inc. is a leading venture-backed biotechnology company focused on the discovery and development of precision medicines for cancer that are directed against a novel class of allosteric mutant oncogenes.

Job Description

Black Diamond Therapeutics is a precision oncology medicine company pioneering the discovery and development of small molecule, tumor-agnostic therapies.

Black Diamond targets undrugged mutations in patients with genetically defined cancers for whom limited treatment options currently exist. Black Diamond is built upon a deep understanding of cancer genetics, protein structure and function, and medicinal chemistry.

The Company’s proprietary technology platform, Mutation-Allostery-Pharmacology, or MAP, platform, is designed to allow Black Diamond to analyze population-level genetic sequencing data to identify oncogenic mutations that promote cancer across tumor types, group these mutations into families and develop a single small molecule therapy in a tumor-agnostic manner that targets a specific family of mutations.

We have an immediate opening for an experienced and highly motivated Lead Computational Scientist to help us build and improve our proprietary AI platform for precision oncology. You will work closely with bioinformaticians and structural proteomics scientists to develop and improve predictive models.


  • Implement and apply structural prediction methods to enhance the power of our machine learning platform
  • Lead scientific collaborations and method development efforts
  • Interact closely with project teams in wider research organization
  • Be a thought leader, stay informed of developments in the field and proactively identify novel scientific approaches



  • PhD in computational biophysics/chemistry, with at least 5-10+ years of relevant work experience in biomolecular simulations. 
  • Expertise in Molecular Dynamics simulations, with a solid knowledge of theory and applications of MD, is required
  • Experience in cloud computing (AWS preferred) is a plus
  • Programming skills are a plus
  • Strong peer-reviewed publication record
  • Ability to independently solve problems, to think critically and creatively as part of a fast-paced research team.
  • Strong communication skills and the ability to communicate results to the research organization

Related Jobs

Associate Director / Director, Clinical Pharmacology

Black Diamond Therapeutics - Cambridge, MA, US

Accounts Payable Specialist

Black Diamond Therapeutics - Cambridge, MA, US

Head of Biometrics - Senior Director Biometrics

Black Diamond Therapeutics - Cambridge, MA, US

Lead Computational Scientist

Black Diamond Therapeutics - Cambridge, MA, US

Associate Director, Technical Operations

Black Diamond Therapeutics - Cambridge, MA, US
Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.