Protein Engineering Research Associate

Caribou Biosciences

Berkeley, CA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Post Date: 12/06/2020
  • Website:
  • Company Address: 2929 7th St Ste 105, Berkeley, CA, 94710

About Caribou Biosciences

Caribou Biosciences is a leading biotechnology company in genome engineering. We develop technology-based solutions for cellular engineering and analysis based on the CRISPR-Cas9 technology platform.

Job Description


Caribou Biosciences, Inc. is a leading clinical-stage company in CRISPR genome engineering located in Berkeley, CA. Caribou's tools and technologies provide transformative capabilities to therapeutic development and the company is advancing an internal pipeline of gene-edited cell therapies for various oncology indications. The eight-year-old company has developed a best-in-class CRISPR genome engineering technology platform and has a leading intellectual property position. At Caribou, every employee is valued for their unique perspective and background. Every person on the Caribou team contributes to problem solving and innovation. The Company’s vision is to advance agile gene editing innovations for the benefit of our communities. 
We are seeking a Research Associate to join our Molecular Engineering group. This role involves providing protein chemistry support to our preclinical programs by playing a key role in advancing our technology platform, developing new biochemical assays, developing purification strategies, and expanding our technological capabilities. You may take on independent projects borne out of collaboration with Scientists and Research Associates across the company. 
Your responsibilities:
  • Operate and maintain FPLC systems
  • Perform protein production, including bacterial expression and purification
  • Analyze purified proteins by methods including biochemical assays and SDS-PAGE
  • Prepare documentation, maintain records, and develop internal quality assurance systems
  • Design and optimize protein expression and purification strategies at a small scale, then scale-up processes as needed
  • Develop new assays and technological capabilities
You should possess the following:
  • An inquisitive approach to science, a positive attitude, and a desire to work collaboratively with colleagues of diverse professional and cultural backgrounds
  • B.Sc. or equivalent in Biochemistry, Bioengineering, Molecular Biology, or a related field
  • Experience in the biotech industry or in an academic, research, or manufacturing laboratory
  • Experience with recombinant protein purification, and chromatography using FPLC systems
  • Strong organizational, time management, and communication skills
Experience in any of these areas is a plus:
  • Bacterial, mammalian, or yeast-based protein expression systems
  • Use of bioreactors for protein expression
  • An understanding of analytical approaches for protein characterization
  • Experience working in a cGMP environment
  • Protein engineering or enzymology
  • M.Sc. or equivalent in Biochemistry, Bioengineering, Molecular Biology or a related field
Caribou Biosciences, Inc. is a dynamic start-up company, and the successful candidate should have a passion for science and a desire to work in a collaborative environment. Caribou promotes a culture in which employees are respected and valued for hard work, innovation, personal initiative, and teamwork.
Caribou offers a comprehensive compensation package, as well as generous paid time off in addition to Company-observed holidays. The Company provides medical, dental, and vision insurance, along with a 401(k) retirement savings plan which includes matching employer contributions.
For more information, please visit Caribou is on Twitter. Sign up to follow our Twitter feed @CaribouBio.
Caribou is an equal opportunity employer and does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law. In addition, Caribou prohibits the harassment of any individual on any of the basis listed above or any other characteristics protected under federal, state, or local laws.
Direct applicants only. No agencies please

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This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.