Research Associate/Senior Research Associate, Cell Biology

Hexagon Bio

Menlo Park, CA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Post Date: 02/16/2021
  • Website: www.hexagonbio.com
  • Company Address: 1505 Adams Drive, Suite A, Menlo Park, CA 94024, US

About Hexagon Bio

Hexagon Bio is a data-driven biotech developing targeted small molecule therapeutics. Our proprietary platform combines data science and synthetic biology to discover and engineer drugs from DNA sequences. We are mining fungal genomes for inspiration for the next generation of targeted therapies for diseases with unmet needs.

Job Description

Company Description

Hexagon Bio is leveraging its proprietary genomics-based platform and understanding of natural product evolution to develop the next generation of medicines for human disease. Hexagon Bio's algorithms identify biosynthetic gene clusters that encode the machinery needed to produce specialized metabolites that can be used to identify and modulate human disease targets. Our unique synthetic biology platform allows us to produce new chemical leads based on these findings. Hexagon’s highly interdisciplinary platform uses data science, genomics, synthetic biology and automation to discover potent, evolutionarily refined small molecules and their cognate targets directly from fungal genomes. 

Job Description

We are looking to add an ambitious cell biologist to our growing drug discovery team. You will use your strength as an experimentalist to design, develop and validate target specific in vitro cell assays. You will document, analyze and interpret experiments testing small molecule candidates and present your results within a multidisciplinary team environment. 

Key Qualifications

  • BS/MS in biology or equivalent field
  • Expertise developing target specific cell assay readouts is required (experience with small molecule flow schemes and screening is a plus)
  • Experience with cell and molecular biology assay technologies, automation methods and visualization of differential gene expression (lentiviral transduction, shRNA, RNAi, FACS, ELISA, Western blotting, HPLC, qRT-PCR, RNA-seq) is desired
  • Familiarity with genome scale gene perturbation methods (genome scale RNAi screens and CRISP-Cas9 methods) desired
  • Experience with various methods to measure target engagement of small molecules in cells
  • Experience in small molecule drug discovery and pharmacology are a plus
  • Strong communication and teamwork skills

Hexagon Bio is an equal opportunity employer and committed to a diverse workplace. All applicants will be considered equally without regard to race, color, ethnicity, veteran status, religion, national origin, marital status, political affiliation, age, sex, sexual orientation, disability status, membership in an organization or any other non-merit factors.

Related Jobs

Hardware Engineer

Hexagon Bio - Menlo Park, CA, US

Research Associate/Senior Research Associate, Cell Biology

Hexagon Bio - Menlo Park, CA, US

Scientist, Cancer Biology

Hexagon Bio - Menlo Park, CA, US

Scientist, Cell Biology

Hexagon Bio - Menlo Park, CA, US

Senior Research Associate, Cell Biology and Drug Discovery

Hexagon Bio - Menlo Park, CA, US
Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.