Research Associate, Engineered Cells


Redwood City, CA, US
  • Job Type: Full-Time
  • Function: Research Sci/Assoc/Mgr
  • Post Date: 04/09/2021
  • Website:
  • Company Address: 3565 Haven Ave, Suite 1, Menlo Park, CA, 94025, US

About Synthego

Synthego is turning molecular biology into an information science. We're building hardware facilities that abstract biological syntheses and research into software.

Our vision is to bring automation to genome engineering, enabling scientists to run their own fully-automated laboratory at low cost, performing millions of controlled, repeatable experiments per day without human error.

Founded by former SpaceX engineers, Synthego is a leading provider of genome engineering solutions. The company’s flagship product, CRISPRevolution, is a portfolio of synthetic RNA designed for CRISPR genome editing and research.

We are venture backed by Founders Fund, Menlo Ventures, 8VC, Intel Capital.

Rev 20170116

Job Description

Synthego is searching for a Research Associate to join our Engineered Cells Operations team and help create the world’s first fully automated Genome Engineering lab.

This position has two shift options available:
- Tuesday through Saturday; 2:30PM-11PM
- Sunday through Thursday; 2:30PM-11PM

What You'll Do

        Engineer immortalized and/or hiPSC cells using CRISPR-Cas9, ultimately generating a pool or clonal population.
        Perform daily cell culture tasks including feeds, expands, and cryopreservation.
        Operate laboratory automation (liquid handling systems, clonal expansion systems) and perform daily operational checks, calibrations, and maintenance as required.
        Extract genomic DNA, perform PCR assembly, and analyze samples using gel electrophoresis or a fragment analyzer.
        Review sequencing data and determine next steps in the manufacturing process.
        Receive and prepare laboratory reagents; update LIMS during the manufacturing process.
        Maintain laboratory inventory, equipment, record-keeping and administrative tasks for cell line maintenance and related projects
        Draft and revise manufacturing standard operating procedures (SOPs) and work instructions (WIs); train junior associates as needed.
        Perform laboratory cleaning and maintenance as per rotation schedule.
        Acquire and analyze microscopy images
        Participate in company meetings and present data and project plans
        Work closely with Process Engineering to define user requirements for new technologies and to execute performance qualification (PQ) experiments.

About You

        BS in biology, molecular and cell biology or related field with a minimum of 1 year of cell culture experience
        Experience working with a variety of immortalized lines,
        Excellent aseptic technique and understanding of contamination control
        Strong organizational, time management, and interpersonal skills
        Excellent verbal and written communication skills
        Ability to deliver cohesive presentations
        Ability to work well within a team and thrive under fast-paced startup environment
        Motivated and looking for a fast paced scientific environment

Nice to Haves

        Experience in fluorescence microscopy and immunostaining techniques preferred.
        Experience with transfections and genetic engineering of mammalian cells preferred
        Direct experience handling induced pluripotent stem cells (iPSC) or primary cells is preferred.
        Experience with flow cytometry preferred

Company Benefits & Perks

        Competitive salary
        Generous equity at an early stage company
        Robust medical, dental and vision benefits
        401k Plan
        Fully stocked kitchen and snacks
        Free catered lunches and dinners
        Onsite gym
        Daily shuttle bus to & from San Francisco

Synthego’s vision is to turn biology into an information science, with the ultimate goal of dramatically extending the healthy human lifespan.

Synthego builds advanced bioinformatics and automated hardware platforms to create next-generation molecular biology tools, starting with full-stack genome engineering.

These world-class tools accelerate basic scientific discovery, critical disease cures and novel synthetic biology applications to improve and prolong life.

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Disclaimer: Local Candidates Only
This company does NOT accept candidates from outside recruiting firms. Agency contacts are not welcome.