Scientist II - Systems Integration at Mission Bio
South San Francisco, CA, US

Summary

Are you curious, driven, and collaborative?  Do you want to work at one of the most innovative and impactful biotech companies in the bay area? We are #2 on the Scientist 2018 Top 10 innovations list. Our mission is to enable our customers to cure cancer.

Mission Bio is a start-up providing the best-in-class solution for single-cell genomics across the range of research and translational/clinical medicine. We are a small team that is growing rapidly, so this is an opportunity for a talented, driven individual to make a significant impact on the direction and success of an exciting young company. We are committed to diversity. If you are a collaborative, curious, hardworking professional who thrives in a fast-paced, dynamic, supportive environment, we would love to meet you.

Mission Bio is a start-up providing the best-in-class solution for single-cell genomics across the range of research and translational/clinical medicine. We are a small team that is growing rapidly, so this is an opportunity for a talented, driven individual to make a significant impact on the direction and success of an exciting young company. We are committed to diversity. If you are a collaborative, curious, hardworking professional who thrives in a fast-paced, dynamic, supportive environment, we would love to meet you.

ESSENTIAL DUTIES AND RESPONSIBILITIES (Other duties may be assigned)

The Assignment…

We are looking for a Systems Integration scientist with a biology focus to execute development activities with the microfluidics team. In this role, the successful candidate will take prototype microfluidics devices and optimize our system’s ability to perform cutting edge single-cell multi-omic analysis. This person will originate solutions and plan experiments, as well as carry out cell prep, the Mission Bio single-cell workflow, NGS library prep, and data analysis/presentation of the results. Specific development projects might include modifying instrument pressure profiles, reagent chemistries, cell prep protocols, and inline assays to achieve new product capabilities. Working daily with a cross-functional team of engineers, biologists, chemists, and bioinformaticians is the norm. This role’s effort will span the product development cycle, from ideation and research through development and launch.

May direct research associates in either a direct or matrix management arrangement.
To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required.

  1. PhD in Molecular Biology / Cell Biology / Biochemistry or associated fields with at least 2+ years of industry biotech experience.
  2. Complete molecular and cellular biology skillset, including cell prep, PCR and DNA quantization techniques.
  3. Experience taking integrated systems (biological, chemical, fluidic, instrument, software) with cross-functional teams through the full product development cycle.
  4. Ability to perform DOE to ensure experimental success, and diligence to execute on those plans.
  5. Intellect and thoroughness to troubleshoot/document prototype systems.
  6. Computational and statistical aptitude to evaluate sequencing results. 
  7. An eager, communicative, and collaborative personality.
  8. NGS and microfluidic experience are bonus.